A Rare Translocation in a Paediatric Myelodysplastic Syndrome
Published: December 1, 2018 | DOI: https://doi.org/10.7860/JCDR/2018/37527.12330
Rachana Kiran Koppalkar, Purnima S Rao, I Sandhya, Muktha R Pai
1. Junior Resident, Department of Pathology, A J Institute of Medical Sciences and Research Centre, Mangalore, Karnataka, India.
2. Associate Professor, Department of Pathology, A J Institute of Medical Sciences and Research Centre, Mangalore, Karnataka, India.
3. Associate Professor, Department of Pathology, A J Institute of Medical Sciences and Research Centre, Mangalore, Karnataka, India.
4. Professor, Department of Pathology, A J Institute of Medical Sciences and Research Centre, Mangalore, Karnataka, India.
Correspondence
Dr. Purnima S Rao,
204, Aadheeshwari Apartments, Mahamaya Temple Road, Field Street, Mangalore-575001, Karnataka, India.
E-mail: pursrao@gmail.com
Myelodysplastic Syndromes (MDS) belong to acquired clonal haematologic disorders associated with defective maturation in erythroid, myeloid and megakaryocytic lineages. It rarely affects children and young adults. The common cytogenetic abnormalities in children are monosomy 7, trisomies 8 and 21. Here, authors report a case of MDS in a 15-year-old patient with a rare finding of chromosomal translocation t (6;9) (p23;q34).
[
FULL TEXT ] | [ PDF]